Белкожаев Аяз Маратович

Научные проекты

Научные проекты

- Исследование циркулирующих микроРНК в качестве биомаркеров нейродегенеративных заболеваний (Айналымдағы микроРНҚ молекулаларын нейродегенеративті аурулардың биомаркерлері ретінде зерттеу).

Публикации

Публикации  в международных рецензируемых научных журналах, входящие в БД Scopus/Web of Science: 

Ashirbekov Y., Abaildayev Arman., Omarbayeva N., Botbayev D., Belkozhayev A., Askandirova Anel., Utegenova G., Sharipov K & Aitkhozhina N. Combination of circulating miR-145-5p/miR-191-5p as biomarker for breast cancer detection. PeerJ. 2020 Dec 16;8: e10494. doi: 10.7717/peerj.10494. PMID: 33362968; PMCID: PMC7749656. WoS: IF 3.06; Q2; Scopus: CiteScore 5.1; SJR 0.695; SNIP 0.894; Percentile 83.

Belkozhayev AM, Al-Yozbaki M, George A, Ye Niyazova R, Sharipov KO, Byrne LJ, Wilson CM. Extracellular Vesicles, Stem Cells and the Role of miRNAs in Neurodegeneration. Curr Neuropharmacol. 2022;20(8):1450–1478. doi: 10.2174/1570159X19666210817150141. PMID: 34414870; PMCID: PMC9881087.  WoS: IF 7.708; Q1; Scopus: CiteScore 9.4; SJR 1.168; SNIP 1.566; Percentile 92.

Belkozhayev A, Niyazova R, Wilson C, Jainakbayev N, Pyrkova A, Ashirbekov Y, Akimniyazova A, Sharipov K, Ivashchenko A. Bioinformatics Analysis of the Interaction of miRNAs and piRNAs with Human mRNA Genes Having di- and Trinucleotide Repeats. Genes (Basel). 2022 Apr 29;13(5):800. doi: 10.3390/genes13050800. PMID: 35627185; PMCID: PMC9141802. WoS: IF 3.05; Q2; Scopus: CiteScore 5.1; SJR 0.924; SNIP 0.941; Percentile 51.

Bekzhan D. Kossalbayev, Girayhan Yilmaz, Asemgul K. Sadvakasova, Bolatkhan K. Zayadan, Ayaz M. Belkozhayev, Gulzhanay K. Kamshybayeva, Gaukhar A. Sainova, Ayshat M. Bozieva, Hesham F. Alharby, Tatsuya Tomo, Suleyman I. Allakhverdiev, Biotechnological production of hydrogen: Design features of photobioreactors and improvement of conditions for cultivating cyanobacteria // International Journal of Hydrogen Energy, 2023. ISSN 0360-3199, https://doi.org/10.1016/j.ijhydene.2023.09.001. WoS: IF 7.139; Q1; Scopus: CiteScore 12.1; SJR 1.318; SNIP 1.423; Percentile 95.

Allakhverdiev ES, Kossalbayev BD, Sadvakasova AK, Bauenova MO, Belkozhayev AM, Rodnenkov OV, Martynyuk TV, Maksimov GV, Allakhverdiev SI. Spectral insights: Navigating the frontiers of biomedical and microbiological exploration with Raman spectroscopy. J Photochem Photobiol B. 2024 Mar;252:112870. doi: 10.1016/j.jphotobiol.2024.112870. Epub 2024 Feb 15. PMID: 38368635. WoS: IF 5.682; Q2; Scopus: CiteScore 9.1; SJR 0.9; SNIP 1.536; Percentile 83.

Zhakypbek Y, Kossalbayev BD, Belkozhayev AM, Murat T, Tursbekov S, Abdalimov E, Pashkovskiy P, Kreslavski V, Kuznetsov V, Allakhverdiev SI. Reducing Heavy Metal Contamination in Soil and Water Using Phytoremediation. Plants (Basel). 2024 Jun 1;13(11):1534. doi: 10.3390/plants13111534. PMID: 38891342; PMCID: PMC11174537. WoS: IF 4.658; Q1; Scopus: CiteScore 5.2; SJR 0.790; SNIP 1.072; Percentile 83.

Belkozhayev A, Niyazova R, Kamal MA, Ivashchenko A, Sharipov K, Wilson CM. Differential microRNA expression in the SH-SY5Y human cell model as potential biomarkers for Huntington's disease. Front Cell Neurosci. 2024 Jul 10;18:1399742. doi: 10.3389/fncel.2024.1399742. PMID: 39049823; PMCID: PMC11267620. WoS: IF 5.05; Q2; Scopus: CiteScore 5.9; Percentile 78. 

Статьи в изданиях, рекомендованных Комитетом по обеспечению качества в сфере науки и высшего образования МНиВО РК:

Belkozhayev A.M., Niyazova R.E., & Ivashchenko, A. T., 2019. The prediction of miRNAs binding sites in CDS mRNA genes having trinucleotide repeats. Experimental Biology, 79(2), 64–74. https://doi.org/10.26577/eb-2019-2-1422.

Belkozhayev A.M., & Niyazova R.Ye., 2020. The interaction of miR-4258, miR-3960, miR-211-3p and miR-3155b with mRNAs genes of non-polyglutamine trinucleotide disorders. News of the National Academy of Sciences of the Republic of Kazakhstan. Series of biology and medicine, 1(337), 25–32. https://doi.org/10.32014/2020.2519-1629.4. DOI:10.32014/2020.2519-1629.4.

Belkozhayev A.M., Niyazova R.E.  Wilson C.M. The features of novel miRNAs interaction with mRNA candidate genes having trinucleotide repeats in coding sequences and untranslated regions //International Journal of Biology and Chemistry. Vol 13.  No 2. 2020. https://doi.org/10.26577/ijbch.2020.v13.i2.04

Международные научно-практические конференции:

Belkozhayev A.M. and Aitkhozhina N.A., Description of the interactions of mRNA and miRNA genes with non-glutamine trinucleotide disorders. The international scientific conference of young scientists: «Fundamental research and innovations in molecular biology, biotechnology, biochemistry» to the 80th anniversary since the birth of Murat Abenovich Aitkhozhin, Ph.D. thesis. M.A. Aitkhozhin Institute of Molecular Biology and Biochemistry. Print Plus, Almaty, Kazakhstan. November 28-29, 2019. p.8.

Belkozhayev A.M. and Niyazova R.Ye., The properties of miRNA interaction with 5’ and 3’ UTR mRNA genes having nucleotide repeats. VII International Scientific and Practical Conference "Biotechnology: Science and Practice", Ph.D. thesis. Polzunov Altai State Technical University. Rospechat, Sevastopol, Russian.  September 16-20, 2019. p. 566.

Belkozhayev A.M. and Niyazova R.Ye., Characteristics of miRNA interaction with CDS mRNA genes associated with CAG trinucleotide repeat disorders development. Moscow Conference on Computational Molecular Biology (MCCMB), Ph.D. thesis. Lomonosov Moscow State University. Institute for Information Transmission Problems, Russian Academy of Sciences, Moscow, Russian.  July 27-30, 2019. p.1-2.

Belkozhayev A.M., The prediction of miRNAs binding sites in CDS mRNA genes having trinucleotide repeats. International Farabi Forum “Al-Farabi and Modernity”: VI International Farabi Readings, Ph.D. thesis. University of KazNU. Al-Farabi Kazakh National Unıversity Press, Almaty, Kazakhstan, April 2-12, 2019. p.287.

Belkozhayev A.M. and Niyazova R.Ye., Features of miRNA binding with mRNA of genes having nucleotide repeats. The proceedings of international congress «Biotechnology: state of the art and perspectives», Ph.D. thesis. Gostiny Dvor. LLC “RED GROUP”, Moscow, Russian. pp. 357-358. February 2 –27, 2019.  pp. 357-358.

Belkozhayev A.M. and Niyazova R.Ye., Features of mirna binding to the mrna genes having nucleotide repeats in the coding region. Materials International scientific conference оf students and young scientists «Farabi alemi», Ph.D. thesis. University of KazNU. Al-Farabi Kazakh National Unıversity Press, Almaty, Kazakhstan. April 7-8, 2020. p.1.

Belkozhayev A.M. and Niyazova R.Ye., Investigating the binding sites of miRNAs on sortilin connected genes deregulation in neurodegenerative diseases. Materials International scientific conference оf students and young scientists «Farabi alemi», Ph.D. thesis. University of KazNU. Al-Farabi Kazakh National Unıversity Press, Almaty, Kazakhstan. April 7-8, 2020. p.2.

Belkozhayev A.M. and Niyazova R.Ye., The сharaсteristiсs оf ID01508.5Р-MIR, ID03332.3Р-MIR and ID02064.5Р-MIR binding sites in mRNA genes having trinuсleоtide reрeats in CDS. Innоvatiоns in life sсienсes: collection of materials of the II International Symposium, Ph.D. thesis. Belgorod State University. GIK, Belgorod, Russian. May 19-20, 2020. р.38-40.

Belkozhayev A.M., Wilson C.M., Sharipov K.O., Ivashchenko A.T., Niyazova R.Ye. In silico prognosis of miRNAs interaction with human mRNA genes having di- and trinucleotide repeats. 1st Central Asia Genomics Symposium. Tashkent, Uzbekistan. December 09-10, 2021. p.47.   

Belkozhayev A.M., Niyazova R.Ye., Sharipov K.O., Wilson C.M. Generation and expression of HTT (Q23 and Q74) in SH-SY5Y cell line. Международной научной конференции «Asfen. Forum, new generation-2023» Almaty, Kazakhstan.  05-06 June, 2023. p.1.

Белкожаев А.М., Шарипов К.О., Ниязова Р.Е. 05-06 июнь, 2023. «Тринуклеотидті CAG қайталымды Гентингтон ауруының биомаркері ретінде адам клеткаларының үлгісіндегі miRNA-дың экспрессияларын профильдеу». Международной научной конференции «Asfen. Forum, new generation-2023» Almaty, Kazakhstan.  05-06 июнь, 2023. p.2.

Патенты:

1. Тыныбеков Б.М., Молдагазыева Ж.Ы., Шарипов К.О., Аширбеков Е.Е., Белкожаев А.М., Бөрібай Э.С., Шаяхметова Ы.Ш. «Ұйқы ауруына» сезімталдылықты анықтау тәсілі. № 4926 на полезную модель от 17.01.2020.

2. Қосалбаев Б.Д., Садвакасова А.К., Залетова Д.Е., Белкожаев А.М., Қамшыбаева Г.Қ., Бауенова М.Ө. Фототрофты микроорганизмдерді дақылдауға арналған фотобиореактор.  № 8207 на полезную модель от 04.04.2023