Berillo Dmitry Alexandrovich
Ph.D.
Associate Professor
Geology and Oil-gas Business Institute named after K. Turyssov
Department of Chemical and Biochemical Engineering
Email: d.berillo@satbayev.111
Professional biography
Dr. Berillo Dmitry Alexandrovich is Ass.Prof. at the Department of chemistry and biochemical engineering, Institute of Chemical and Biological Technologies (IHBT), Satbayev University Almaty 050013, Kazakhstan. Recently he involved in research mobility of 3 months (September-December, 2022) in the framework of the “Santé Kazakhstan-Ouzbekistan" individual fellowship program in the Center for Materials Forming (CEMEF) of Mines Paris (France). The title of the research project is “Development of functionalized biobased cryogels and aerogels using noncovalent interactions”. The overall objectives of the mobility include exchange of knowledge in the area of drug delivery system and polymer chemistry. From october 2021 until January 2023 he held a position Deputy Head of the Research Institute of Fundamental and Applied Medicine after B.A. Atchabarova. From October 2019 till October 2021 he had been head of the Department of pharmaceutical and Toxicological chemistry, pharmacognosy and botany at School of Pharmacy KazMNU. He has a research and teaching experience of 13 years, as well as has more than 40 scientific publications in international journals with an impact factor https://orcid.org/0000-0003-2534-9367, the H- index-19 https://scholar.google.com/citations?user=Jg_qLEoAAAAJ&hl=en
He has performed the teaching load of the department, taught the academic disciplines in Russian and English: pharmaceutical chemistry, general methods of industrial synthesis, chemistry and technology of synthetic medicinal substances. He acquired fundamental knowledge in the field of organic synthesis of pharmaceutically active compounds. In total, he synthesized and described in detail more than 100 new potentially pharmacologically active compounds, and for some of them, metered-dose drug delivery systems were developed(co-author of 9 patents of the Republic of Kazakhstan). http://kzpatents.com/patents/berillo-dmitrijj-aleksandrovich From 2010 to the present his main research focus has been the development of various macroporous materials that can be successfully applied to various tasks of tissue engineering and regenerative medicine. He has extensive experience in the development of cryogels based on various synthetic and natural polymers, which will be an excellent basis for solving various problems of regenerative medicine, including the restoration of intervertebral disc tissue. Internships in leading research groups: biomaterials and biosensors, Lund University (Sweden, 2010-2012) https://lup.lub.lu.se/search/person/biot-dbo and Capsenze HB biosensors for early diagnosis of diseases including HIV and heart disease (2012-2014, Sweden), University of Brighton (2016-2018, UK) work related to Microbiology and biomaterials https://www.britishcouncil.kz/newton-al-farabi/achievements and Aarhus University (2018-2019, Denmark) work related to Microbiology and biosensors and self-healing concrete with microorganisms https://watec.au.dk/research/sensor-development-and-applications/research-portraits/dmitriy-berillo/ . These internships gave Dr Berillo a fundamental understanding of radical, photo-and electro-polymerization for creating biomaterials, as well as additional experimental knowledge and experience in Microbiology and biochemistry. From January 2015 to September 2016, he worked as a senior researcher at the laboratory of Biosensors and bio-Tools, national Laboratory Astana, Center for Science and Life, Nazarbayev University (Astana). Dr. Berillo's research was devoted to the creation of modern methods for rapid and effective diagnosis of tuberculosis and various types of cancer.
Dr. Berillo has experience in successfully managing projects "Microencapsulation of probiotics in polysaccharide matrices for the development of functional foods based on Mare's milk" 2018-2020 MES RK (co-Director); "Impedance biosensor for detection of Mycobacterium tuberculosis 2015-2017" MES RK (co-Director). "Development of a flow bioreactor based on 3D-structured bacteria for biodegradation of aromatic chlorine derivatives in polluted water" " Immobilized noble metal nanoparticles as an effective flow catalyst”British Council Newton - al-Farabi Partnership program 2015 (head).
In the field of scientific interests of others. Berillo includes a synthesis of the farm. drugs, peptides and their derivatives, incentive-based hydrogels, hydrogels with metered drug delivery, and macroporous biocompatible and biodegradable materials. Recent work by others. Berillo and co-authors studied the differentiation of mesenchymal stem cells derived from mouse bone marrow into osteoblasts within a new biocompatible framework with immobilized growth factor. Additional to the current research is the creation of highly effective dressings with plant extracts for the treatment of chronic wounds.
Currently Dr. Dmitriy A. Berillo is Guest Editor of the Processes(IF: 3.352) Special Issue: New Sights into Porous Organic Polymers https://www.mdpi.com/journal/processes/special_issues/2ZBWY2PMGJ , and Frontiers in Chemistry (5.545) "Extractable biologically active compounds from plants". Previously he served as Guest Editor of the Special Issue "Advances in Cryogels" Journal Gels) https://www.mdpi.com/journal/gels/special_issues/advances_cryogels
Scientific research of Berillo D. A. received international recognition.
According to the results of the report of the Independent Accreditation and Rating Agency (NAAR) in 2020, he entered the top 10 in the list of the 50 best scientists of the Republic of Kazakhstan. The rating of University teachers "TOP-50" is formed by quality indicators made by universities according to the key parameters of indicators for evaluating the competitiveness of BA and PhD educational programs. https://iaar.agency/rating/1/0/2020#dflip-report_1/1/ page 23 Winner of the "Best Teacher 2020" award of the Ministry of Education and Science of the Republic of Kazakhstan. "The best scientific researcher in medicine" of the Ministry of Health of the Republic of Kazakhstan 2021. The winner of the project "BEST IN EDUCATION - 2021" among the best specialists in education was awarded the medal "Best teacher 2021" for his contribution to the development of education and a diploma of the first degree organized by the "National organisation "Bobek"
In 2018, the IUPAC organization Berillo D. A. entered the 100 best young chemists in the world https://iupac.org/100/pt-of-chemist/#dmitriy-berillo-b
In 2016-2018, the winner of the prestigious individual European Grant of Marie Curie (Curie Individual Fellowship 2016-2018) https://www.brighton.ac.uk/aquatic/research-projects/cryo-bacteria-reactor.aspx
Winner of the gold medal from WIPO (World intellectual property organization in the "youngest inventor" category (Almaty-Geneva 2010). https://shapagat.kazpatent.kz/ru/content/berillo-dmitriy-aleksandrovich
Awards for the best oral presentations at international conferences:
1) ICEWW 2017 19th International Conference on Environment, Water and Wetlands May 2017 (Montreal, Canada);
2) European Advanced Materials Congress Stockholm, Sweden, August – 2018
3) 7th International Conference on Advances in Skin, Wound Care and Tissue Science, Sept, 2019 Copenhagen, Denmark.
Education
2007-2010 Doctorate in chemical sciences (GPA 3.87) Dept of organic chemistry and chemistry of natural compounds,Kazakh National University al-Farabi (KazNU), Almaty, KZ.
2005-2007 Master's Degree in chemical sciences (GPA 3.95) KazNU Al-Farabi, Almaty, KZ
2001-2005 Bachelor's Degree in chemical sciences (GPA 4.0) KazNU Al-Farabi, Almaty, KZ
2021 Professional retraining diploma of additional education «Industrial Pharmacy in the field of production of drugs» online course 550h Modern Scientific Technical academy, Moscow Russia
2021 Certificate of additional education by “Toxicological Chemistry” online course 144h LLP” Academy of pedagogical Education” Moscow Russia
Scientific projects
Main works:
https://nur.nu.edu.kz/bitstream/handle/123456789/1337/avtoref%20Berillo.pdf?sequence=1&isAllowed=y
https://lup.lub.lu.se/search/person/biot-dbo
YouTube channel with research related talks at international online conferences and videolectures. https://www.youtube.com/watch?v=mKZdfOqlpIk&list=PLBW_3hyp9s1mpwMmDgaWJxcJUFe9jtMvJ
Publications
I N. Savina, L Otero-Gonzalez, D Berillo Chapter Macroporous cryogel-based systems for water treatment applications: nanocomposite-based cryogels and bacteria-based bioreactors. Singapore, 2023 editor P. V. Mohanan and Sudha Kappalli (Eds): Biomedical Applications and Toxicity of Nanomaterials, 978-981-19-7833-3, 537319_1_En, (Chapter 1) 902р
Tauanov, Z., Zakiruly, O., Baimenova, Z., Baimenov, A., Akimbekov, N. S., & Berillo, D. (2023). Antimicrobial and Antiviral Properties of Triclosan-Containing Polymer Composite: Aging Effects of pH, UV, and Sunlight Exposure. Polymers, 15(5), 1236. https://www.mdpi.com/2073-4360/15/5/1236
Berillo, D., Kozhahmetova, M., & Lebedeva, L. (2022). Overview of the Biological Activity of Anthraquinons and Flavanoids of the Plant Rumex Species. Molecules, 27(4), 1204. https://www.mdpi.com/1420-3049/27/4/1204
Muhammad Moazzam , Ahmer Shehzad , Dana Sultanova , Fariza Mukasheva, Alexander Trifonov , Dmitriy Berillo , Dana Akilbekova Macroporous 3D printed structures for regenerative medicine applications.Bioprinting, 2022, 28, e00254 https://doi.org/10.1016/j.bprint.2022.e00254
Berillo, D. A., & Dyusebaeva, M. A. (2022). Synthesis of hydrazides of heterocyclic amines and their antimicrobial and spasmolytic activity. Saudi Pharmaceutical Journal, 30(7), 1036-1043.https://scholar.google.com/citations?view_op=view_citation&hl=ru&user=Jg_qLEoAAAAJ&sortby=pubdate&authuser=1&citation_for_view=Jg_qLEoAAAAJ:NaGl4SEjCO4C
Tauanov, Z., Zakiruly, O., Baimenova, Z., Baimenov, A., Akimbekov, N. S., & Berillo, D. (2022). Antimicrobial Properties of the Triclosan-Loaded Polymeric Composite Based on Unsaturated Polyester Resin: Synthesis, Characterization and Activity. Polymers, 14(4), 676.
Berillo, D. A., & Savina, I. N. (2023). Cryogels with Noble Metal Nanoparticles as Catalyst for “Green” Decomposition of Chlorophenols. Inorganics, 11(1), 23. https://www.mdpi.com/2304-6740/11/1/23
Berillo, D. (2022). Comparative Toxicity of Interferon Beta-1a Impurities of Heavy Metal Ions. Medicina, 58(4), 463. https://www.mdpi.com/1648-9144/58/4/463
Seidakhmetova, R. B., Amanzhan, A., Shults, E. E., Goldaeva, K. V., Adekenov, S. M., & Berillo, D. (2022). Analgesic and Antidepressant Activity of 8-Substituted Harmine Derivatives. Chemistry of Heterocyclic Compounds, 58(6-7), 324-332. https://link.springer.com/article/10.1007/s10593-022-03092-9
Jandosov, J., Alavijeh, M., Sultakhan, S., Baimenov, A., Bernardo, M., Sakipova, Z., ... & Berillo, D. (2022). Activated Carbon/Pectin Composite Enterosorbent for Human Protection from Intoxication with Xenobiotics Pb (II) and Sodium Diclofenac. Molecules, 27(7), 2296.
Chaplin, J. D., Berillo, D., Purkis, J. M., Byrne, M. L., Tribolet, A. D. C. C. M., Warwick, P. E., & Cundy, A. B. (2022). Effective 137Cs+ and 90Sr2+ immobilisation from groundwater by inorganic polymer resin Clevasol® embedded within a macroporous cryogel host matrix. Materials Today Sustainability, 19, 100190. https://www.sciencedirect.com/science/article/pii/S2589234722000823
Volkova N., Berillo D.Water sorption isotherms of cryogels based on gelatine and oxidised dextran. Gels IF4.7, Q1 2021 https://www.mdpi.com/2310-2861/7/4/159
Berillo D., Zh. Zharkinbekov, Y. Kim, K. Raziyeva, K. Temirkhanova and A. Saparov Progress in the Development of Stimuli-Responsive Polymers for Drug Delivery Review Pharmaceutics Q1, 2021
Berillo D., A. Yeskendir, Zh. Zharkinbekov, K. Raziyeva, and A. Saparov, Peptide-Based Drug Delivery Systems Review Medinica Q2, 2021
Caplin JL., Al-Jwaid AKA. and Berillo D. Macroporous cryogels crosslinked with bacteria for the bio-remediation of contaminants in water. 2021. Review paper. IF 3.426,Q1, Percentile 70 Polymers 2021
A Zh. Baimenov, I R. Fakhradiyev, D. A. Berillo,T.M. Saliyev, T S. Nurgozhin and V J. Inglezakis Macroporous polymer antidotes for treatment of rats intoxicated by LD50 dose of heavy metals Molecules 2021
Fapyane, D; Berillo D; Marty, Jean-Louis; Revsbech, Niels Peter Urea biosensor based on CO2 microsensor ASC Omega 2020IF2.6
Dollerup Nielsen S., Wolfgang Hansen M., H. Røy, Urup Kjeldsen K., Berillo D. Identifying polyextremophilic bacterial strains and pH responsive superabsorbent polymers for subsurface self-healing cementitious materials, in preparation. 2023
Chaplin J.D., Warwick P.E., Berillo D. et al. A high-performance 3-D macroporous polyborane composite cryogels for selective 137Cs+ and 90Sr2+ immobilisation from ground water. 2022
Berillo D. Gold nanoparticles incorporated into cryogel walls for decomposition of 4-nitrophenol. J. of Clean Production. Oct 2019 IF9
Sultankulov B., Berillo D., et al. Progress in the development of chitosan-based biomaterials for tissue engineering and biomedical application. Review paper, Biomolecules IF4.5 Aug 2019
Berillo D., Savina I. et al. Cryobacteriareactor for bioremediation of phenol derivatives. Water Research. 2019, 153, P. 324-334. IF 7.9
Baimenov Zh, Berillo D and Inglezakis V.J. Novel cryogels for mercury (II) removal from water: synthesis, characterization and sorption mechanisms. Hazarad Materials (2020) Р 123056. 2020 IF10.5 Q1, Percentile 98 https://www.sciencedirect.com/science/article/pii/S0304389420310451 Q1
Baimenov A., Berillo D. and Inglezakis V. A review of cryogel applications in the adsorptive removal of heavy metals from aqueous solutions. Advances in Colloid and Interface Science. 2019 IF13
A. Zh. Baimenov, D.A. Berillo, V.J. Inglezakis Cryogel-based nanocomposites for iodide removal from water Molecular Liquids 2020 6.3
Berillo and Cundy A. Cryogels cross-linked by metal coordinated complexes. In situ formation of Pd and Pt nanoparticles and their catalytic activity. Carbohydrate polymers. 2018, 192, P. 166-175 IF 9,3 Q1, Percentile 95 corresponding author
Al-Jwaid* AK, Berillo* D et al. Monolithic of crosslinked bacterial cells cryogel for phenol degradation manuscript in preparation, *Both authors contributed equally. RCS Advances. 2018, 8 (54), P. 30813-30824. IF3.0.
Akilbekova D., Shaimerdenova M., Adilov S. and Berillo D. Biocompatible scaffolds for regenerative medicine. International (Int) journal of biological macromolecules. 2018, 114, P. 324-333. IF 6.95, Q1, Percentile 84
Baimenov A, Berillo D. et al. Novel amphoteric cryogels for Cd2+ ions removal from aqueous solutions. International Conference on Key Engineering Materials (ICKEM) 2018. 775, P. 376-382 IF0.35 Q3-Q4
Sekula jr P, Bačik M, Mosej J, Sekula sr P, Berillo D. etc. Elimination of 2-chlorophenol by two types of iron particles Materials Today: Proceedings 2018, 5 (11), P. 22889-22893. Percentile 46, Q3, IF0.97
Ertürk G, Berillo D., Hedström M. and Mattiasson B. Microcontact-bsa imprinted capacitive biosensor for real-time, sensitive and selective detection of BSA. Journal Biotechnology Reports. 2014, 3, P. 65-72. IF 3.26.
Berillo D., Mattiasson B. and Kirsebom H. Cryogelation of chitosan using noble metal ions: In situ formation of nanoparticles. Biomacromolecules. 2014, 15(6), P. 2246-55. Q1, IF 6.09, Percentile 96
Berillo D. and Volkova N. Preparation and physicochemical characteristics of macroporous hydrogel based on gelatin and oxidized dextran. Journal of material science. 2014, 49(14), P. 4855-68. Q1, IF 3.442, Percentile 80
Zaushitsyna O., Berillo D. et al. Cryostructured and crosslinked viable cells forming monoliths suitable for bioreactor applications. Topics in catalysis. 2014, P. 1-10. Q1 IF2.4, Percentile 74
Aragão R., Zaushitsyna O., Berillo D. et al. Immobilization of Clostridium acetobutylicum DSM 729 as macroporous aggregates through cryogelation for butanol production. Process Biochemistry. 2013, P. 10-18. IF 3,1
Berillo D., Elowsson L. and Kirsebom H. Oxidized dextran as crosslinker for chitosan cryogel scaffolds and formation of polyelectrolyte complexes between chitosan and gelatin. Macromolecular bioscience. 2012. 12 (8), P. 1090-1099. Q1, IF 3,41, Percentile 88
Kirsebom H., Elowsson L., Berillo D. et al. Enzyme-catalyzed crosslinking in a partly frozen state: A new way to produce supermacroporous protein structures. Macromolecular bioscience. 2012, 13, P. 67-76. Q1, IF 3,41,Percentile 88
Kudaibergenov S., Berillo D. Adilov Zh., Tatykhanova G.,Sadakbaeva Zh., Abdullin Kh., Galaev I.Novel macroporous amphoteric gels: preparation and characterization eXPRESS Polymer Letters, V.6, (2012) N.5 p.346–353 Q1 IF 3,083, Percentile 85
Tatykhanova G., Berillo D. Sadakbayeva Zh., Galaev I., Abdullin K.,Adilov S., Kudaibergenov S.Metal complexes of amphoteric cryogels based on allylamine and methacrylic acid Macromolecular Symposia (2012), 317, 1, 18–27. IF 0.68, Q3,
Berillo D., Mattiasson B., Galaev I. and Kirsebom H. Formation of Macro-porous Self-Assembled Hydrogels through Cryogelation of Fmoc-Phe-Phe. J. Colloid and Interface Science. 2012, 368, P.226-230. Q1 IF 7.48 Percentile 93
Berillo D.A., and KADYRGALIEV B. REVIEW OF RECENT ADVANCES IN THE USE OF DRUG DELIVERY SYSTEMS IN OPHTHALMOLOGY Reviews and Advances in Chemistry 2023 10.1134/S2634827623600081
Berillo D.A., Dyusebaeva M.A. Berganayeva A.E., Berganayeva G.E., Ibragimova N.A., Jumabayeva S.M., Kudaibergenov N.Zh., Kanapiyeva А.M., Kirgizbayeva A.A. and Vassilina G.K. Antimicrobial Activity of Silver Nanoparticles Stabilized by Liposolble Extract of Artemisia terrae-albae MDPI Processes 2023 October Q2 corresponding author
Mukasheva, F ; Moazzam, M; Yernaimanova, B; Shehzad, A; Zhanbassynova, A; Berillo, D and Akilbekova, D, 3d Printed Hydrogel Scaffold with Gradient Structure for Improved Stem Cells Osteodifferentiation. Available at SSRN: https://ssrn.com/abstract=4536366 or http://dx.doi.org/10.2139/ssrn.4536366
M Zhurinov, D. Berillo*, Bazhikova B K, K D Rakhimov, T Bekezhanova Estimation of antiviral activity and toxicity of biologically active substances from the raw materials of Artemisia cina Berg. in vitro and in vivo corresponding author Q1 Molecules https://www.mdpi.com/1420-3049/28/14/5413
А Khamitova, D Berillo, A Lozynskyi, Yu Konechnyi, D Mural, V Georgiyants «Biological activity of thiadiazole derivatives» BMS-MRMC-2023-113 Mini-Reviews in Medicinal Chemistry IF3.7 ISSN (Print): 1389-5575 ISSN (Online): 1875-5607 2023 Q2 DOI: 10.2174/1389557523666230713115947
Berillo D. Synthesis and properties of α- and β-aminopropanoic acid hydrazide derivatives Monograph 251 pages; 2023
D. Berillo & Aknazar A. Macroporous adsorbent for removal of silver nanoparticles from waste water Processes 2023, 11, 1661. https://doi.org/10.3390/pr11061661 Q2 corresponding author
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Potential research studies of doctoral students
Khamitova A.E. «Synthesis of new pharmaceutical substances based on nitrogen-containing heterocyclic compounds» Department of Pharmaceutical and Toxicological chemistry, Pharmacognosy and botany School of Pharmacy at Asfendiyarov Kazakh National Medical University 2020- present
Kadyrgaliev Baurzhan. Educational program, "Medicine " "Development of a medical device for the treatment of macular edema in age-related macular degeneration" Asfendiyarov Kazakh National Medical University 2021-2024
Ermuhametova Asel. Educational program, Pharm technology “Development and research of macroporous enterosorbents for biomedical purposes” School of Pharmacy at Asfendiyarov Kazakh National Medical University 2022- 2025.
If you are inspired, self-motivated and interested to do the cutting edge research in following fields of science: drug delivery, biomaterials, enterosorbents or adsorbents for water purification using MOFs and other metaloorganic frameworks, microbiology, analytical chemistry please contact me. #ZhasGalym #research #science #biomaterials #pharmacy #3Dprinting #plastic #polymers #nanotechnologies #nanoparticles