Kossalbayev Bekzhan Duisenbiuly

Scientific projects

AP13067574 “Increasing the activity of hydrogen production by cyanobacteria strains using genetic engineering methods”, 2022-2024, CMU.

AP26193911 «Scientific substantiation, development and testing of synthetic microbiomes from bacteria producing ACC deaminase to reduce ethylene stress in plants» (GF 2025-2027)

Publications

[1] Kossalbayev B.D., Kakimova A.B., Sadvakasova A.K., Bauenova M.O., Balouch H., Lyaguta M.A., Ahmad F., Kirbayeva D.K., Ozgul S., Allakhverdiev S.I. Strategies for genetic modification of microalgae to improve the production efficiency of liquid biofuel. Int. J. Hydrogen Energy 2025;100:1301–14. https://doi.org/10.1016/j.ijhydene.2024.12.306

[2] Kossalbayev B.D., Wei M., Wang J., Pang Y., Lv M., Sadvakasova A.K., Bauenova M.O., Zhang X., Zhao W., Xu S., Huang Z. Growth promotion of synthetic microbial communities influenced by the function, diversity and interactions of their constituent strains and soil types. World J. Microbiol. Biotechnol. 2025;41(6):181. https://doi.org/10.1007/s11274-025-04403-w

[3] Kamshybayeva G.K., Sadvakasova A.K., Belkozhayev A.M., Kossalbayev B.D., Bauenova M.O., Zharmukhamedov S.K., Hou H.J.M., Allakhverdiev S.I. Progress and innovation in key technologies for converting biomass to hydrogen. Int. J. Hydrogen Energy 2025;113:90–106. https://doi.org/10.1016/j.ijhydene.2025.02.437

[4] Kirbayeva D.K., Shayakhmetova A.Y., Kossalbayev B.D., Sadvakasova A.K., Bauenova M.O. Harnessing MicroRNAs and CRISPR to enhance biofuel production in microalgae. Int. J. Hydrogen Energy 2025;157:150399. https://doi.org/10.1016/j.ijhydene.2025.150399

[5] Kurmanbek A., Shagyrbay A., Kudaiberdi B., Mussabekov M.N., Kossalbayev B.D. Sufi Motives in Ancient Turkic Nomadic Culture. Pharos J. Theol. 2025;106(Special Issue-2):1–13. https://doi.org/10.46222/pharosjot.106.2030

[6] Nygymetova A.M., Sadvakasova A.K., Zaletova D.E., Kossalbayev B.D., Bauenova M.O., Wang J., Huang Z., Sarsekeyeva F.K., Kirbayeva D.K., Allakhverdiev S.I. Development and Transfer of Microbial Agrobiotechnologies in Contrasting Agrosystems: Experience of Kazakhstan and China. Plants 2025;14(14):2208. https://doi.org/10.3390/plants14142208

[7] Sadanov A.K., Baimakhanova B.B., Orasymbet S.E., Ratnikova I.A., Turlybaeva Z.Z., Baimakhanova G.B., Amitova A.A., Omirbekova A.A., Aitkaliyeva G.S., Kossalbayev B.D., Belkozhayev A.M. Engineering useful microbial species for pharmaceutical applications. Microorganisms 2025;13(3):599. https://doi.org/10.3390/microorganisms13030599

[8] Sadvakasova A.K., Kossalbayev B.D., Zaletova D., Bauenova M.O., Huang Z., Zharmukhamedov S.K., Shabala S., Allakhverdiev S.I. Combating phytopathogens by integration of metagenomics and phototrophic biotechnologies: Toward sustainable agricultural practices. Crit. Rev. Plant Sci. 2025;44(2):70–87. https://doi.org/10.1080/07352689.2025.2494872

[9] Zhakypbek Y., Belkozhayev A.M., Kerimkulova A., Kossalbayev B.D., Murat T., Tursbekov S., Turysbekova G., Tursunova A., Tastambek K.T., Allakhverdiev S.I. MicroRNAs in plant genetic regulation of drought tolerance and their function in enhancing stress adaptation. Plants 2025;14(3):410. https://doi.org/10.3390/plants14030410

[10] Zhakypbek Y., Rakhmetullina A., Kamarkhan Z., Tursbekov S., Shi Q., Xing F., Pyrkova A., Ivashchenko A., Kossalbayev B.D., Belkozhayev A.M. In silico analysis of miRNA-mRNA binding sites in Arabidopsis thaliana as a model for drought-tolerant plants. Plants 2025;14(12):1800. https://doi.org/10.3390/plants14121800

[11] Kossalbayev B.D., Yilmaz G., Ozcan H.G., Soykan G., Yalcin S., Allakhverdiev S.I. Photosynthesis and hydrogen energy for sustainability: Harnessing the sun for a greener future. Photosynthetica 2024;62(2):138–46. https://doi.org/10.32615/ps.2024.013

[12] Kossalbayev B.D., Yilmaz G., Sadvakasova A.K., Zayadan B.K., Belkozhayev A.M., Kamshybayeva G.K., Sainova G.A., Bozieva A.M., Alharby H.F., Tomo T., Allakhverdiev S.I. Biotechnological production of hydrogen: Design features of photobioreactors and improvement of conditions for cultivating cyanobacteria. Int. J. Hydrogen Energy 2024;49:413–32. https://doi.org/10.1016/j.ijhydene.2023.09.001

[13] Abuhena M., Zhakypbek Y., Yerlan U., Aben A., Kamarkhan Z., Allakhverdiev S.I., Assemgul S.K., Al Rashid J., Karim M.D., Kuanysh T.T., Belkozhayev A.M., Kossalbayev B.D. An overview of Bacillus species in agriculture for growth promotion, biocontrol and dry tolerance. ES Food Agrofor. 2024;18:1321. https://doi.org/10.30919/esfaf1321

[14] Allakhverdiev E.S., Kossalbayev B.D., Sadvakasova A.K., Bauenova M.O., Belkozhayev A.M., Rodnenkov O.V., Martynyuk T.V., Maksimov G.V., Allakhverdiev S.I. Spectral insights: Navigating the frontiers of biomedical and microbiological exploration with Raman spectroscopy. J. Photochem. Photobiol. B 2024;252:112870. https://doi.org/10.1016/j.jphotobiol.2024.112870

[15] Bauenova M.O., Sadvakasova A.K., Kossalbayev B.D., Yilmaz G., Huang Z., Wang J., Balouch H., Zaletova D.E., Lyaguta M.A., Alharby H.F., Allakhverdiev S.I. Optimising microalgae-derived butanol yield. Int. J. Hydrogen Energy 2024;49:593–601. https://doi.org/10.1016/j.ijhydene.2023.11.065

[16] Bauenova M.O., Sarsekeyeva F.K., Sadvakasova A.K., Kossalbayev B.D., Mammadov R., Token A.I., Balouch H., Pashkovskiy P., Leong Y.K., Chang J.-S., Allakhverdiev S.I. Assessing the efficacy of cyanobacterial strains as Oryza sativa growth biostimulants in saline environments. Plants 2024;13(17):2504. https://doi.org/10.3390/plants13172504

[17] Kamshybayeva G., Kossalbayev B.D., Huang Z., Bauenova M.O., Allakhverdiev S.I. Hydrogen production with a newly discovered cyanobacteria strain. BIO Web Conf. 2024;100:02022. https://doi.org/10.1051/bioconf/202410002022

[18] Kamshybayeva G.K., Kossalbayev B.D., Sadvakasova A.K., Bauenova M.O., Zayadan B.K., Krapivina A.A., Sainova G.A., Alharby H.F., Allakhverdiev S.I. Effect of the photosynthesis inhibitors on hydrogen production by non-heterocyst cyanobacterial strains. Int. J. Hydrogen Energy 2024;52:167–82. https://doi.org/10.1016/j.ijhydene.2023.03.453

[19] Kamshybayeva G.K., Kossalbayev B.D., Sadvakasova A.K., Kakimova A.B., Bauenova M.O., Zayadan B.K., Lan C.-W., Alwasel S., Tomo T., Chang J.-S., Allakhverdiev S.I. Genetic engineering contribution to developing cyanobacteria-based hydrogen energy to reduce carbon emissions and establish a hydrogen economy. Int. J. Hydrogen Energy 2024;54:491–511. https://doi.org/10.1016/j.ijhydene.2022.12.342

[20] Mahmoudi H., Kossalbayev B.D., Sarsekeyeva F., Zaletova D., Lyaguta M. The influence of varying concentrations of CO2 on the buildup of carbohydrates in microalgae biomass. BIO Web Conf. 2024;100:02013. https://doi.org/10.1051/bioconf/202410002013

[21] Sandybayeva S.K., Kossalbayev B.D., Zayadan B.K., Kopecký J., Kakimova A.B., Bolatkhan K., Allakhverdiev S.I. Isolation, identification and pigment analysis of novel cyanobacterial strains from thermal springs. Plants 2024;13(21):2951. https://doi.org/10.3390/plants13212951

[22] Sarsekeyeva F.K., Sadvakasova A.K., Sandybayeva S.K., Kossalbayev B.D., Huang Z., Zayadan B.K., Akmukhanova N.R., Leong Y.K., Chang J.-S., Allakhverdiev S.I. Microalgae- and cyanobacteria-derived phytostimulants for mitigation of salt stress and improved agriculture. Algal Res. 2024;82:103686. https://doi.org/10.1016/j.algal.2024.103686

[23] Yilmaz G., Sadvakasova A.K., Kossalbayev B.D., Bauenova M.O., Zharmukhamedov S.K., Ziyayeva G.K., Zaletova D.E., Alharby H.F., Allakhverdiev S.I. Hydrogen energy development in Turkey: Challenges and opportunities. Int. J. Hydrogen Energy 2024;52:1304–11. https://doi.org/10.1016/j.ijhydene.2023.11.230

[24] Zhakypbek Y., Kossalbayev B.D., Belkozhayev A.M., Murat T., Tursbekov S., Abdalimov E., Pashkovskiy P., Kreslavski V., Kuznetsov V., Allakhverdiev S.I. Reducing heavy metal contamination in soil and water using phytoremediation. Plants 2024;13(11):1534. https://doi.org/10.3390/plants13111534

[25] Balouch H., Zayadan B.K., Sadvakasova A.K., Kossalbayev B.D., Bolatkhan K., Gencer D., Civelek D., Demirbag Z., Alharby H.F., Allakhverdiev S.I. Prospecting the biofuel potential of new microalgae isolates. Int. J. Hydrogen Energy 2023;48(50):19060–73. https://doi.org/10.1016/j.ijhydene.2023.02.028

[26] Kamshybayeva G.K., Kossalbayev B.D., Sadvakasova A.K., Bauenova M.O., Zayadan B.K., Bozieva A.M., Alharby H.F., Tomo T., Allakhverdiev S.I. Screening and optimisation of hydrogen production by newly isolated nitrogen-fixing cyanobacterial strains. Int. J. Hydrogen Energy 2023;48(44):16649–62. https://doi.org/10.1016/j.ijhydene.2023.01.163

[27] Sadvakasova A.K., Kossalbayev B.D., Bauenova M.O., Balouch H., Leong Y.K., Zayadan B.K., Huang Z., Alharby H.F., Tomo T., Chang J.-S., Allakhverdiev S.I. Microalgae as a key tool in achieving carbon neutrality for bioproduct production. Algal Res. 2023;72:103096. https://doi.org/10.1016/j.algal.2023.103096

[28] Sadvakasova A.K., Bauenova M.O., Kossalbayev B.D., Zayadan B.K., Huang Z., Wang J., Balouch H., Alharby H.F., Chang J.-S., Allakhverdiev S.I. Synthetic algocyanobacterial consortium as an alternative to chemical fertilizers. Environ. Res. 2023;233:116418. https://doi.org/10.1016/j.envres.2023.116418

[29] Kossalbayev B.D., Kakimova A.B., Bolatkhan K., Zayadan B.K., Sandybayeva S.K., Bozieva A.M., Sadvakasova A.K., Alwasel S., Allakhverdiev S.I. Biohydrogen production by novel cyanobacterial strains isolated from rice paddies in Kazakhstan. Int. J. Hydrogen Energy 2022;47(37):16440–53. https://doi.org/10.1016/j.ijhydene.2022.03.126

[30] Allakhverdiev E.S., Khabatova V.V., Kossalbayev B.D., Zadneprovskaya E.V., Rodnenkov O.V., Martynyuk T.V., Maksimov G.V., Alwasel S., Tomo T., Allakhverdiev S.I. Raman spectroscopy and its modifications applied to biological and medical research. Cells 2022;11(3):386. https://doi.org/10.3390/cells11030386

[31] Kamshybayeva G.K., Kossalbayev B.D., Sadvakasova A.K., Zayadan B.K., Bozieva A.M., Dunikov D., Alwasel S., Allakhverdiev S.I. Strategies and economic feasibilities in cyanobacterial hydrogen production. Int. J. Hydrogen Energy 2022;47(69):29661–84. https://doi.org/10.1016/j.ijhydene.2022.06.277

[32] Sadvakasova A.K., Kossalbayev B.D., Token A.I., Bauenova M.O., Wang J., Zayadan B.K., Balouch H., Alwasel S., Leong Y.K., Chang J.-S., Allakhverdiev S.I. Influence of Mo and Fe on photosynthetic and nitrogenase activities of nitrogen-fixing cyanobacteria under nitrogen starvation. Cells 2022;11(5):904. https://doi.org/10.3390/cells11050904

[33] Sadvakasova A.K., Kossalbayev B.D., Zayadan B.K., Kirbayeva D.K., Alwasel S., Allakhverdiev S.I. Potential of cyanobacteria in the conversion of wastewater to biofuels. World J. Microbiol. Biotechnol. 2021;37(8):140. https://doi.org/10.1007/s11274-021-03107-1

[34] Kossalbayev B.D., Tomo T., Zayadan B.K., Sadvakasova A.K., Bolatkhan K., Alwasel S., Allakhverdiev S.I. Determination of the potential of cyanobacterial strains for hydrogen production. Int. J. Hydrogen Energy 2020;45(4):2627–39. https://doi.org/10.1016/j.ijhydene.2019.11.164

[35] Bolatkhan K., Sadvakasova A.K., Zayadan B.K., Kakimova A.B., Sarsekeyeva F.K., Kossalbayev B.D., Bozieva A.M., Alwasel S., Allakhverdiev S.I. Prospects for the creation of a waste-free technology for wastewater treatment and utilization of carbon dioxide based on cyanobacteria for biodiesel production. J. Biotechnol. 2020;324:162–70. https://doi.org/10.1016/j.jbiotec.2020.10.010

[36] Sadvakasova A.K., Kossalbayev B.D., Zayadan B.K., Bolatkhan K., Alwasel S., Najafpour M.M., Tomo T., Allakhverdiev S.I. Bioprocesses of hydrogen production by cyanobacteria cells and possible ways to increase their productivity. Renew. Sustain. Energy Rev. 2020;133:110054. https://doi.org/10.1016/j.rser.2020.110054

[37] Bolatkhan K., Kossalbayev B.D., Zayadan B.K., Tomo T., Veziroglu T.N., Allakhverdiev S.I. Hydrogen production from phototrophic microorganisms: Reality and perspectives. Int. J. Hydrogen Energy 2019;44(12):5799–811. https://doi.org/10.1016/j.ijhydene.2019.01.092

[38] Zayadan B., Usserbayeva A., Bolatkhan K., Akmukhanova N., Kossalbayev B.D., Baizhigitova A., Los D. Screening of isolated and collection strains of cyanobacteria on productivity for determining their biotechnological potential. Eur. J. Entomol. 2018;55(2):121–30. https://doi.org/10.26577/EJE-2018-2-823